Other pre-clinical tools

Here we have summarised other pre-clinical tools for use in PTEN research that have been generated with the support of the Foundation.

Professor Rafael Pulido’s group at the Biocruces Bizkaia Health Research Institute, Spain, has generated anti-PTEN monoclonal antibodies that target the C2 domain of PTEN. Contrary to many other anti-PTEN antibodies that target the C-terminal tail, these antibodies can be used to assess the levels of PTEN isoforms that possess both missense and nonsense mutations. Antibodies are available to researcher on request from the Pulido laboratory.

This project received funding from PTEN Research.

For further information and access to antibodies, please contact rpulidomurillo@gmail.com

Torices et al., 2022, Torices et al., 2023